![]() For example, over-the-counter pain relievers like Aspirin (acetylsalicylic acid) can pack upwards of 40–60 mg in a single tablet ( 6).įinally, certain performance-enhancing formulas like pre-workout supplements may have high amounts of caffeine, with up to 250 mg in just 2 teaspoons (10 grams). Still, it contains very low amounts of caffeine, at 2–7 mg per cup (240 mL) ( 4, 5).įurthermore, pay attention to medications, supplements, and personal care products that may harbor caffeine. Foods and beverages with caffeine include coffee, tea, energy drinks, soda, dark chocolate, and some ice creams and desserts.ĭecaf coffee is a good option if you still want to enjoy the flavor and health benefits of coffee. If you notice uncomfortable symptoms like shakiness, stop consuming caffeine immediately. Stop caffeinating as soon as you notice adverse effects Nonetheless, you can take a few steps to minimize its side effects. The only way to get rid of it is to wait for it to naturally flush itself. ![]() In fact, once it has entered your body, there’s not much you can do to flush caffeine out. Imminent cardiac arrest in caffeine toxicity should prompt intra-lipid therapy to scavenge the free serum caffeine.Caffeine’s effects are known to last for several hours - and you may have stronger jitters if you drank a lot of coffee, soda, energy drink, or some other caffeinated beverage ( 3). Caffeine exhibits ideal characteristics to be dialyzed, including low protein binding (36%), low molecular size (194), and a small volume of distribution (0.6 to 0.8 L/kg). Hemodialysis has been effective in severe, life-threatening caffeine ingestions. Īctivated charcoal can bind caffeine if the ingestion is recent, and repeated doses can help diminish serum levels via the enterohepatic circulation. Vasopressors, such as vasopressin or phenylephrine, can be used to maintain blood pressure (goal mean arterial pressure greater than 65 mm Hg) without worsening tachycardia. Procainamide, lidocaine, or bicarbonate have also been utilized for the treatment of tachydysrhythmias. Beta-blockade with esmolol is useful for tachycardia. Hydration may be oral in minor cases, yet severe cases benefit from intravenous (IV) hydration. The primary treatment for minor caffeine ingestion is supportive. įatal caffeine overdose is relatively uncommon, and treatment data is limited to case reports. Cardiac monitoring allows evaluation of heart rate and early recognition of dysrhythmias such as ventricular ectopy or fibrillation. An electrocardiogram may demonstrate tachycardia, ST-segment depressions, or T-wave inversions. It is also important to obtain serum myoglobin and creatine kinase levels to monitor for rhabdomyolysis. Caffeine toxicity can result in hypokalemia, hypocalcemia, hyponatremia, and hyperglycemia. Ī venous blood gas may demonstrate anion gap metabolic acidosis, which can be severe. Lethal blood levels are typically above 80 to 100 mg/L, although one case occurred at 15 mg/L. ![]() Although not available in all hospitals, serum caffeine levels are generally obtained with an immunoassay. Serum caffeine levels can guide prognosis and therapy. Routine serum laboratory evaluations can be useful in drug overdose cases, especially in the setting of unstable vital signs, seizures, or altered sensorium. ![]()
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